Online ISSN: 1945-4589
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About Aging
Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

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Predicting Brain Age With Machine Learning and Transcriptome Profiling

Aging

March 21, 2024
In this study, researchers investigated age-associated gene expression changes in the prefrontal cortex of male and female brains and used machine learning to develop age prediction models. continue reading »

FoxO6-mediated ApoC3 Upregulation Promotes Hepatic Steatosis and Hyperlipidemia in HFD Aged Rats

Aging

March 20, 2024
PRESS RELEASE: On March 3, 2024, a new research paper was published in Aging's Volume 16, Issue 5, entitled, “FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in aged rats fed a high-fat diet.” continue reading »

PR55α-controlled PP2A Inhibits p16 Expression and Blocks Cellular Senescence Induction

Aging

March 19, 2024
PRESS RELEASE: On March 4, 2024, a new research paper was published in Aging's Volume 16, Issue 5, entitled, “PR55α-controlled protein phosphatase 2A inhibits p16 expression and blocks cellular senescence induction by γ-irradiation.” continue reading »

Genome-wide Transcriptome Profiling and Development of Age Prediction Models in the Human Brain

Aging

March 15, 2024
PRESS RELEASE: A new research paper was published on the cover of Aging's Volume 16, Issue 5, entitled, “Genome-wide transcriptome profiling and development of age prediction models in the human brain.” continue reading »

Transcriptomic Modulation of Alzheimer’s Disease by Activated Protein C Using Single-Cell RNA-Seq

News

March 13, 2024
PRESS RELEASE: A new research paper was published in Aging's Volume 16, Issue 4, entitled, “Single-Cell RNA-seq reveals transcriptomic modulation of Alzheimer’s disease by activated protein C.” continue reading »