Impact of Dual Immunotherapies Before Surgery in HR+/HER2-negative Breast Cancer

Oncotarget | June 20, 2024
In this new study, researchers assessed the feasibility of treating HR+/HER2-negative breast cancer patients with the immunotherapies durvalumab and tremelimumab before standard neoadjuvant chemotherapy and surgery. continue reading »

Dr. Blagosklonny’s Strategy: From Osimertinib to Preemptive Combinations

Oncotarget | June 6, 2024
This article dissects Dr. Mikhail V. Blagosklonny’s paradigm-shifting perspective on preemptive combinations for treating EGFR-mutant non-small cell lung cancer. continue reading »

Combating Doxorubicin-Resistant Acute Myeloid Leukemia

Oncotarget | May 23, 2024
In this new study, researchers examined the impact of MIA-602 as monotherapy and in combination with Doxorubicin on three Doxorubicin-resistant acute myeloid leukemia cell lines. continue reading »

Targeting Mitophagy as a Therapeutic Strategy for Cancer Treatment

Aging | June 28, 2024
In this new study, researchers investigated the intricate link between mitophagy and cancer stem cells. continue reading »

Werner Syndrome and the Power of Proteomics

Aging | June 13, 2024
In this new study, researchers used proteomics to investigate Werner syndrome and proteins associated with age and/or genotype. continue reading »

When Does Human Life Truly Begin?

Aging | May 16, 2024
In this fascinating new review, researchers Polina A. Loseva and Vadim N. Gladyshev from Harvard Medical School discuss the beginning of becoming a human. continue reading »

The Role of CDKs in Breast Cancer Among Women in Pakistan

Genes & Cancer | October 28, 2022
Researchers examined the mRNA expression levels of six CDKs in Pakistani women with pre- and postmenopausal breast cancer with lung metastasis. continue reading »

Cell Cycle Mechanism as Potential Target to Treat Array of Cancers

Genes & Cancer | September 12, 2022
In a recently published Genes & Cancer review paper, researchers discuss the role of CDK4 in cell cycle control, normal development, tumorigenesis, and cancer therapeutics. continue reading »

Common Bacteria Associated With Gastric Cancer and New Biomarkers

Genes & Cancer | August 19, 2022
Researchers investigated the expression of two lncRNAs in gastric cancer tissues and evaluated their association with a common strain of bacteria. continue reading »