Online ISSN: 1945-4589
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About Aging
Launched in 2009, Aging publishes papers of general interest and biological significance in all fields of aging research and age-related diseases, including cancer—and now, with a special focus on COVID-19 vulnerability as an age-dependent syndrome. Topics in Aging go beyond traditional gerontology, including, but not limited to, cellular and molecular biology, human age-related diseases, pathology in model organisms, signal transduction pathways (e.g., p53, sirtuins, and PI-3K/AKT/mTOR, among others), and approaches to modulating these signaling pathways.

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IL-17 Promotes IL-18 Production in Osteoarthritis Synovial Fibroblasts Via…

Aging

February 13, 2024
PRESS RELEASE: A new research paper was published in Aging’s Volume 16, Issue 2, entitled, “IL-17 promotes IL-18 production via the MEK/ERK/miR-4492 axis in osteoarthritis synovial fibroblasts.” continue reading »

PROX1/α-SMA Correlated With Colorectal Cancer Progression, Poor Outcomes and Therapeutic Resistance

News

February 7, 2024
PRESS RELEASE: A new research paper was published in Aging's Volume 16, Issue 2, entitled, “PROX1 interaction with α-SMA-rich cancer-associated fibroblasts facilitates colorectal cancer progression and correlates with poor clinical outcomes and therapeutic resistance.” continue reading »

Epigenetic Drift Underlies Epigenetic Clock Signals, but…

Aging

February 6, 2024
PRESS RELEASE: A new research paper was published in Aging's Volume 16, Issue 2, entitled, “Epigenetic drift underlies epigenetic clock signals, but displays distinct responses to lifespan interventions, development, and cellular dedifferentiation.” continue reading »

Senescence-Related TME Genes as Key Prognostic Predictors in HNSCC

Aging

February 1, 2024
In a new study, researchers aimed to investigate the prognostic significance of senescence-related TME genes in head and neck squamous cell carcinoma (HNSCC) and their potential implications for immunotherapy response.  continue reading »

Prognostic Significance of Senescence-related TME Genes in Head and Neck Squamous Cell Carcinoma

Aging

January 31, 2024
PRESS RELEASE: A new research paper was published on the cover of Aging’s Volume 16, Issue 2, entitled, “Prognostic significance of senescence-related tumor microenvironment genes in head and neck squamous cell carcinoma.” continue reading »